Basic Information
VIS ID
TVIS44010993
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
42532844/42063641 (Hg38)
End
42532844/42063641 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/5111250; hsa-mir-1185-1/Downstream/5697354;
Nearest TSS
ENST00000550708/Upstream/364214; ENST00000554042/Downstream/204945;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/456515, chr14-CpG: 22/Downstream/2823828
Upstream sequence
ATAAAACATGGTTCATTTTTAGAATCTTGTAGTTATATATAATAGTTGTAATGTAAAAATATATGAATTCTTTTTTCCCTTTTTCTTGCAACTTCAaggg
Downstream sequence
tacatgtgcaggtttgttatatggtaaattgcatgtcacagggctttggtgtacagattattttgtcaccgagatgatgagcatggtacccaagaggtag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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