Basic Information
VIS ID
TVIS44010998
Fusion event
HTLV-1-LOC105370491 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
51321212/50854494 (Hg38)
End
51321212/50854494 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105370491
Nearest miRNA
hsa-mir-208a/Upstream/554548; hsa-mir-1185-1/Downstream/3093933;
Nearest TSS
ENST00000550708/Upstream/6372; ENST00000555292/Downstream/17666;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/22735, chr14-CpG: 61/Downstream/17500
Nearby gene
ABHD12B(+17666) ;
Upstream sequence
gattaaataacttaataacatacaaagcatttccctttgtaggtgctatgtaactgtcagCTACCTCATTTTAAGCAGTGGTTTCACTGTGGCCAACACA
Downstream sequence
TCCATAACCGGTGTCCTAGAGGcagaggtggattcactgtgaaggtagagtcctcaggtgccatgccccttccaggtgtctgagaggggccctcacactg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate