Basic Information
VIS ID
TVIS44011060
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
65732115/65698212 (Hg38)
End
65732115/65698212 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/7925860; hsa-mir-11401/Downstream/1504109;
Nearest TSS
ENST00000527434/Upstream/96514; ENST00000568023/Downstream/165572;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/574451, chr16-CpG: 40/Downstream/572170
Nearby gene
LINC00922(No orient, 121912)
Upstream sequence
GCAATAGGGACAGCTGCTTCCCAGATTCTGTTCATTGTCCTCCATGTTAGAGAATTTATCTTAAGAAACCACGTggccgggcgcggtggctcatgtctgt
Downstream sequence
aatcccagcacttttggaggcggaggagggcggaccacgaggtcaggagatcgagaccatcctggctaactcagtgacaccccgtctctactaaaaatgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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