Basic Information
VIS ID
TVIS44011061
Fusion event
HTLV-1-C16orf86 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
67702509/67668606 (Hg38)
End
67702509/67668606 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA16B
Target gene
C16orf86
Nearest miRNA
hsa-mir-1225/Upstream/466211; hsa-mir-11401/Downstream/564820;
Nearest TSS
ENST00000527434/Upstream/1298; ENST00000562633/Downstream/8878;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1155, chr16-CpG: 60/Downstream/50340
Upstream sequence
CGAGGTGGATAAGTCAACCCAGGTGGACATCGACAAGATGCTGAGTGTCTGCACTGCTCCACTTGTCCCCCCGCTCTCTCCTCAGTACAAGTGACTGTCC
Downstream sequence
CGCCCCACTGGTGGCTCCCCTCCTTCCACGCCTGAATTTGGCTTCAGGCTTCCTGTGGGCCTAGGCCCTCTGGTGGCGGGGGCAAATTTGGCACCTGCCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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