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Viral Integration Site DataBase
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TVIS44011064
Basic Information
VIS ID
TVIS44011064
Fusion event
HTLV-1-NUDT7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
77765127/77731230 (Hg38)
End
77765127/77731230 (Hg38)
Orient
-
Location type
Intronic
Target gene
NUDT7
miRNAs that regulate target gene
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6514-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-548s
;
hsa-mir-3926
;
hsa-mir-4470
;
hsa-mir-4786-5p
;
hsa-mir-3190-5p
;
hsa-mir-6849-3p
;
hsa-mir-942-3p
;
hsa-mir-1273d
;
hsa-mir-548as-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-7641
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-623
;
hsa-mir-6780b-3p
;
hsa-mir-4780
;
hsa-mir-3938
;
hsa-mir-4748
;
hsa-mir-4464
;
hsa-mir-4762-3p
;
hsa-mir-3192-3p
;
hsa-mir-3171
;
hsa-mir-194-5p
;
hsa-mir-4502
;
hsa-mir-627-3p
;
hsa-mir-411-3p
;
hsa-mir-379-3p
;
hsa-mir-590-3p
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-4722-5p
;
hsa-mir-4768-3p
;
hsa-mir-4804-3p
;
hsa-mir-6808-5p
;
hsa-mir-6893-5p
;
hsa-mir-7162-3p
;
hsa-mir-940
Nearest miRNA
hsa-mir-1225/Upstream/862211; hsa-mir-11401/Downstream/3653788;
Nearest TSS
ENST00000527434/Upstream/8685;
ENST00000564031/Downstream/6175;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/8446
,
chr16-CpG: 65/Downstream/57248
Upstream sequence
tcatattttaaaaatcattgcccagctcaaGGATAACATTTTCTTGAGAGCAATGTTCTCACTAATCCAAAATGATCTTTTCCAATTCCTATTACCTATT
Downstream sequence
AATTGGAATAGGTGTACAAGGCAAATTGAATAAAATTGGTATGCTATGAGATACTTTTGAAACCTTTCAAAATAcagtcatgtgctgcaaaactgttttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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