Basic Information
VIS ID
TVIS44011074
Fusion event
HTLV-1-PHF12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
End
27272584/28945566 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-320b ; hsa-mir-454-3p ; hsa-mir-652-3p ; hsa-mir-92a-3p ; hsa-mir-1184 ; hsa-mir-138-2-3p ; hsa-mir-486-3p ; hsa-mir-513c-5p ; hsa-mir-514b-5p ; hsa-mir-328-5p ; hsa-mir-3688-5p ; hsa-mir-6880-5p ; hsa-mir-6721-5p ; hsa-mir-6809-5p ; hsa-mir-766-5p ; hsa-mir-6077 ; hsa-mir-4722-5p ; hsa-mir-4795-5p ; hsa-mir-6743-5p ; hsa-mir-4459 ; hsa-mir-4688 ; hsa-mir-3925-5p ; hsa-mir-31-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6778-5p ; hsa-mir-6799-5p ; hsa-mir-1233-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-4779 ; hsa-mir-6753-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-4671-3p ; hsa-mir-6073 ; hsa-mir-4668-5p ; hsa-mir-298 ; hsa-mir-5681a ; hsa-mir-20b-3p ; hsa-mir-5584-5p ; hsa-mir-3158-5p ; hsa-mir-142-3p ; hsa-mir-4295 ; hsa-mir-130b-3p ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130a-3p ; hsa-mir-4713-5p ; hsa-mir-3156-3p ; hsa-mir-188-3p ; hsa-mir-6794-3p ; hsa-mir-6837-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-205-5p ; hsa-mir-3162-3p ; hsa-mir-4301 ; hsa-mir-4639-3p ; hsa-mir-483-3p ; hsa-mir-3064-3p ; hsa-mir-5701 ; hsa-mir-668-3p ; hsa-mir-6890-3p ; hsa-mir-4773 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-7703 ; hsa-mir-6807-5p ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-4264 ; hsa-mir-1273g-3p ; hsa-mir-3934-5p ; hsa-mir-552-3p ; hsa-mir-7156-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1304-3p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-28-3p ; hsa-mir-3171 ; hsa-mir-34c-3p ; hsa-mir-513b-3p ; hsa-mir-548ac ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-548bb-3p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548j-3p ; hsa-mir-548x-3p ; hsa-mir-548z ; hsa-mir-576-3p
Nearest miRNA
hsa-mir-1180/Upstream/83836; hsa-mir-10226/Downstream/445096;
Upstream sequence
ACGCGGAGGCAAATGCTACAGAAATCTGTCTGACGGGAAGGGACCATGCTGAGGTCTGCCGAGGTAGATGCACTTCTCTATCAGACCATTTTGGTCCCTC
Downstream sequence
AGTCTGTTTGGAGCAAAATGCCATAAGAAGGTAATCACAGGAAACCAGTCAGTTTTATCATCCTGATTACTGATGCCCCATGGTATTCACTCTGTCAATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate