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TVIS44011074
Basic Information
VIS ID
TVIS44011074
Fusion event
HTLV-1-PHF12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
27272584/28945566 (Hg38)
End
27272584/28945566 (Hg38)
Orient
+
Location type
Intronic
Target gene
PHF12
miRNAs that regulate target gene
hsa-mir-221-3p
;
hsa-mir-320b
;
hsa-mir-454-3p
;
hsa-mir-652-3p
;
hsa-mir-92a-3p
;
hsa-mir-1184
;
hsa-mir-138-2-3p
;
hsa-mir-486-3p
;
hsa-mir-513c-5p
;
hsa-mir-514b-5p
;
hsa-mir-328-5p
;
hsa-mir-3688-5p
;
hsa-mir-6880-5p
;
hsa-mir-6721-5p
;
hsa-mir-6809-5p
;
hsa-mir-766-5p
;
hsa-mir-6077
;
hsa-mir-4722-5p
;
hsa-mir-4795-5p
;
hsa-mir-6743-5p
;
hsa-mir-4459
;
hsa-mir-4688
;
hsa-mir-3925-5p
;
hsa-mir-31-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6778-5p
;
hsa-mir-6799-5p
;
hsa-mir-1233-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-765
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-6822-5p
;
hsa-mir-6750-5p
;
hsa-mir-4779
;
hsa-mir-6753-5p
;
hsa-mir-203b-3p
;
hsa-mir-7158-3p
;
hsa-mir-4671-3p
;
hsa-mir-6073
;
hsa-mir-4668-5p
;
hsa-mir-298
;
hsa-mir-5681a
;
hsa-mir-20b-3p
;
hsa-mir-5584-5p
;
hsa-mir-3158-5p
;
hsa-mir-142-3p
;
hsa-mir-4295
;
hsa-mir-130b-3p
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130a-3p
;
hsa-mir-4713-5p
;
hsa-mir-3156-3p
;
hsa-mir-188-3p
;
hsa-mir-6794-3p
;
hsa-mir-6837-3p
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-150-5p
;
hsa-mir-205-5p
;
hsa-mir-3162-3p
;
hsa-mir-4301
;
hsa-mir-4639-3p
;
hsa-mir-483-3p
;
hsa-mir-3064-3p
;
hsa-mir-5701
;
hsa-mir-668-3p
;
hsa-mir-6890-3p
;
hsa-mir-4773
;
hsa-mir-5582-3p
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-7703
;
hsa-mir-6807-5p
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-4264
;
hsa-mir-1273g-3p
;
hsa-mir-3934-5p
;
hsa-mir-552-3p
;
hsa-mir-7156-3p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-1304-3p
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-28-3p
;
hsa-mir-3171
;
hsa-mir-34c-3p
;
hsa-mir-513b-3p
;
hsa-mir-548ac
;
hsa-mir-548ae-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548d-3p
;
hsa-mir-548h-3p
;
hsa-mir-548j-3p
;
hsa-mir-548x-3p
;
hsa-mir-548z
;
hsa-mir-576-3p
Nearest miRNA
hsa-mir-1180/Upstream/83836; hsa-mir-10226/Downstream/445096;
Nearest TSS
ENST00000595228/Upstream/770;
ENST00000578748/Downstream/4291;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/42406
,
chr17-CpG: 193/Downstream/3635
Upstream sequence
ACGCGGAGGCAAATGCTACAGAAATCTGTCTGACGGGAAGGGACCATGCTGAGGTCTGCCGAGGTAGATGCACTTCTCTATCAGACCATTTTGGTCCCTC
Downstream sequence
AGTCTGTTTGGAGCAAAATGCCATAAGAAGGTAATCACAGGAAACCAGTCAGTTTTATCATCCTGATTACTGATGCCCCATGGTATTCACTCTGTCAATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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