Basic Information
VIS ID
TVIS44011076
Fusion event
HTLV-1-LRRC37BP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
28915047/30588029 (Hg38)
End
28915047/30588029 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LRRC37BP1
Nearest miRNA
hsa-mir-1180/Upstream/470857; hsa-mir-10226/Downstream/506321;
Nearest TSS
ENST00000595228/Upstream/22453; ENST00000581019/Downstream/139535;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/110354, chr17-CpG: 113/Downstream/12045
Upstream sequence
catgagccaccatgcctggcTATTAATTTTTTAAGTGATCATTTACACAGCAATGTTGGTGAACTTTCTGATTCATAAattttttgcttccctaataaac
Downstream sequence
cttataactctaatttatttttcttgccttataatgatggcaaagacttccaatactacaattaaatgtagctttgacaatggctatctttgcctttttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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