Basic Information
VIS ID
TVIS44011079
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
38117251/39960998 (Hg38)
End
38117251/39960998 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/234437; hsa-mir-10226/Downstream/65334;
Nearest TSS
ENST00000595228/Upstream/7735; ENST00000577447/Downstream/1975;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7590, chr17-CpG: 66/Downstream/19405
Nearby gene
GSDMA(+1975) ;
Upstream sequence
CACACACAGCAGGTTTCTATGTAAATATGTGCTTGTGATAGGGACCAGATGACTAACGACAACCttttttttctttttcttttttttttttttgaatcgg
Downstream sequence
agtcttgctctgtcgcccagcctggcatgcagtggcacgatctcggctcactgcaacctccacctcccgggttcaagtgattctcctgcctcagcctccc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate