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VISDB
Viral Integration Site DataBase
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TVIS44011086
Basic Information
VIS ID
TVIS44011086
Fusion event
HTLV-1-VMP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
57845827/59768466 (Hg38)
End
57845827/59768466 (Hg38)
Orient
-
Location type
Intronic
Target gene
VMP1
miRNAs that regulate target gene
hsa-mir-210-3p
;
hsa-mir-1-3p
;
hsa-mir-16-5p
;
hsa-mir-296-3p
;
hsa-mir-25-3p
;
hsa-mir-4776-3p
;
hsa-mir-744-3p
;
hsa-mir-4659b-5p
;
hsa-mir-4659a-5p
;
hsa-mir-5590-5p
;
hsa-mir-7159-5p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-4694-5p
;
hsa-mir-5186
;
hsa-mir-7978
;
hsa-mir-181a-3p
;
hsa-mir-5685
;
hsa-mir-4690-3p
;
hsa-mir-1324
;
hsa-mir-4709-5p
;
hsa-mir-4272
;
hsa-mir-6856-3p
;
hsa-mir-513b-3p
;
hsa-mir-505-3p
;
hsa-mir-421
;
hsa-mir-3161
;
hsa-mir-622
;
hsa-mir-4761-5p
;
hsa-mir-624-3p
;
hsa-mir-132-3p
;
hsa-mir-212-3p
;
hsa-mir-4482-3p
;
hsa-mir-7159-3p
;
hsa-mir-138-2-3p
;
hsa-mir-4282
;
hsa-mir-4698
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6873-3p
;
hsa-mir-555
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6845-3p
;
hsa-mir-3925-3p
;
hsa-mir-766-3p
;
hsa-mir-5680
;
hsa-mir-4506
;
hsa-mir-150-3p
Nearest miRNA
hsa-mir-10226/Upstream/402312; hsa-mir-1250/Downstream/72800;
Nearest TSS
ENST00000595228/Upstream/33128;
ENST00000591877/Downstream/5288;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/60719
,
chr17-CpG: 73/Downstream/124215
Upstream sequence
ccaaggcaggtggatcacctgaggtcaggagttcgagaccagccggaccaacatggtgaaaccccatctctactgaaaatataaaacttagctgggcatg
Downstream sequence
gtggtgggtgcctgtagtcactgctactcgggatgctgaggcaggagaatcgcttgaacccaggaggtggaggttgcagtgagctgagatcacaccattg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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