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TVIS44011115
Basic Information
VIS ID
TVIS44011115
Fusion event
HTLV-1-CD226 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
67557996/69890760 (Hg38)
End
67557996/69890760 (Hg38)
Orient
-
Location type
Intronic
Target gene
CD226
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-1277-5p
;
hsa-mir-3924
;
hsa-mir-223-5p
;
hsa-mir-190a-3p
;
hsa-mir-511-3p
;
hsa-mir-380-3p
;
hsa-mir-411-3p
;
hsa-mir-379-3p
;
hsa-mir-4495
;
hsa-mir-5011-5p
;
hsa-mir-6798-3p
;
hsa-mir-6793-3p
;
hsa-mir-323b-3p
;
hsa-mir-4640-3p
;
hsa-mir-5582-3p
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-516b-5p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-6516-3p
;
hsa-mir-630
;
hsa-mir-6832-3p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-421
;
hsa-mir-505-3p
;
hsa-mir-7159-5p
;
hsa-mir-676-5p
;
hsa-mir-16-1-3p
;
hsa-mir-4709-5p
;
hsa-mir-212-3p
;
hsa-mir-132-3p
;
hsa-mir-5706
;
hsa-mir-4782-5p
;
hsa-mir-1299
;
hsa-mir-129-5p
;
hsa-mir-8055
;
hsa-mir-744-3p
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-6880-5p
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-4294
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-6812-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-2681-5p
;
hsa-mir-511-5p
;
hsa-mir-6830-3p
;
hsa-mir-892a
;
hsa-mir-1227-3p
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-2467-3p
;
hsa-mir-25-3p
;
hsa-mir-32-5p
;
hsa-mir-3612
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-377-5p
;
hsa-mir-4257
;
hsa-mir-4325
;
hsa-mir-4497
;
hsa-mir-4537
;
hsa-mir-4710
;
hsa-mir-4792
;
hsa-mir-5186
;
hsa-mir-550b-2-5p
;
hsa-mir-6086
;
hsa-mir-650
;
hsa-mir-6511a-5p
;
hsa-mir-7703
;
hsa-mir-7855-5p
;
hsa-mir-92a-3p
;
hsa-mir-92b-3p
Nearest miRNA
hsa-mir-1-2/Upstream/2809074; hsa-mir-548av/Downstream/2962561;
Nearest TSS
ENST00000575820/Upstream/151775;
ENST00000578377/Downstream/5049;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/420748
,
chr18-CpG: 80/Downstream/314525
Upstream sequence
CAGTTAGAAAAAGGAGAAAGTAGGAAAGTGTGAGTGTTTTGAGGCAGTGGAAAGCACAAACTGAGATTCAAATCATGCTGACAGTATCTCTCTACCCTGT
Downstream sequence
GTAGGACACCTTTGTGCCTACAAAGGTAGGTGGATCAGTGGCCTATGACCCATCACTGATCccaggaccaggtggcttcacagatgaattctatcaaaca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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