Basic Information
VIS ID
TVIS44011124
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q11
Reference genome
GRCh37/hg19
Start
27855302/27364394 (Hg38)
End
27855302/27364394 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10395/Upstream/6965040; hsa-let-7e/Downstream/7758306;
Nearest TSS
ENST00000633603/Upstream/3217693; ENST00000588318/Downstream/276244;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3392437, chr19-CpG: 42/Downstream/429226
Upstream sequence
agatgaatgcacacatcacagtgaagtttatcagaatgcttctgtctaatttttaagtgaagatatattctttttcaccataggcctcaaaaccctccaa
Downstream sequence
atatccacttgcagattatacaaaaagactgtttctaaacagctcaatcaaaaagaaggttcaactctgtgagatgaaagcatacatcacaaagaagttc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate