Basic Information
VIS ID
TVIS44011148
Fusion event
HTLV-1-EHBP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
GRCh37/hg19
Start
63056751/62829616 (Hg38)
End
63056751/62829616 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
EHBP1
miRNAs that regulate target gene
hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1301/Upstream/623699; hsa-mir-10b/Downstream/1511131;
Nearest TSS
ENST00000437798/Upstream/122424; ENST00000462441/Downstream/28822;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/123398, chr2-CpG: 24/Downstream/215376
Upstream sequence
gttgctgcaaatgccattattttgttcctttttaaggctgagtggtgttctatgttgtgtgtgtgtgtgtgtgtgtgtgtatatatatattatatataat
Downstream sequence
actactatatataatacataatactactatatatactactatatattatatatagtggtattgtgtatatataatatataatatataataatatataaat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate