Basic Information
VIS ID
TVIS44011162
Fusion event
HTLV-1-LINC01885 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
108055638/107439182 (Hg38)
End
108055638/107439182 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LINC01885
Nearest miRNA
hsa-mir-1285-2/Upstream/5006816; hsa-mir-10b/Downstream/1702308;
Nearest TSS
ENST00000437798/Upstream/57990; ENST00000439893/Downstream/90305;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/551422, chr2-CpG: 16/Downstream/105063
Nearby gene
MIR548AU(No orient, 89657)
Upstream sequence
tctgcaggtgtgaagaatgcaagcattctggtggcatggcttcctctacctagattttaaaggatgaacctgctacaacagagtgtcccaactaaggcaa
Downstream sequence
agccttatagagctgtgggaaaggggccacctcaaagactccagaactatagagtcaccagcatccaacaccagcctgggagagctgcaaggactgagcc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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