Basic Information
VIS ID
TVIS44011163
Fusion event
HTLV-1-SH3RF3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
109952713/109336257 (Hg38)
End
109952713/109336257 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
SH3RF3
Nearest miRNA
hsa-mir-1285-2/Upstream/22632; hsa-mir-10b/Downstream/733704;
Nearest TSS
ENST00000437798/Upstream/206909; ENST00000356454/Downstream/231596;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/205880, chr2-CpG: 246/Downstream/277072
Upstream sequence
CTTACTACTCTGGGAAGTTCAAAAATCACCACGTGCCTAGAAGCTGGCCTGCAGGAGAAGGATTCTCCCTCACTGGGGAAGAGGTGTCATGCTGGGAAGG
Downstream sequence
CTGTCTTGTTCTCTAGACTAGGTAAAATGACAACCAAAGACCCATTTTTACTTTAAAATGAGTTTACAAAGCCACATTAAAGTGTGAAGGCTTCAAGAAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate