Basic Information
VIS ID
TVIS44011207
Fusion event
HTLV-1-LOC100128988 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q12
Reference genome
GRCh37/hg19
Start
39651265/41022625 (Hg38)
End
39651265/41022625 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC100128988
Nearest miRNA
hsa-mir-103a-2/Upstream/2505993; hsa-mir-1-1/Downstream/146398;
Nearest TSS
ENST00000382410/Upstream/324009; ENST00000361337/Downstream/6193;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/329618, chr20-CpG: 150/Downstream/5796
Nearby gene
TOP1(+6197) ;
Upstream sequence
GACTACTTTTCTTGCCCCAAGCCACATGGCCAGGATCCTACATCTTTGTTGCTTGACTGCCTCTCATTTCATAATTCAAGAGTTGCCAGCTTTCTTATTG
Downstream sequence
ATACTGACCttttttttttttttttttgagatggagtttccctctcgttgcccaggctggagtgcaatggcgcaatctcggctcactgcaacctccacct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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