VISDB Viral Integration Site DataBase

VIS ID

TVIS44011250

Fusion event

HTLV-1-TMEM184B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

38629713/38233707 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-15a-5p ; hsa-mir-124-3p ; hsa-mir-877-5p ; hsa-mir-484 ; hsa-mir-92a-3p ; hsa-let-7c-5p ; hsa-mir-4323 ; hsa-mir-3972 ; hsa-mir-1202 ; hsa-mir-3194-5p ; hsa-mir-7158-3p ; hsa-mir-4539 ; hsa-mir-1225-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-7113-5p ; hsa-mir-646 ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-1299 ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4326 ; hsa-mir-3659 ; hsa-mir-574-5p ; hsa-mir-3663-5p ; hsa-mir-7152-3p ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-518c-5p ; hsa-mir-323b-3p ; hsa-mir-3607-5p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-1324 ; hsa-mir-3937 ; hsa-mir-4726-3p ; hsa-mir-6077 ; hsa-mir-6511b-5p ; hsa-mir-6801-5p ; hsa-mir-6811-5p ; hsa-mir-1184 ; hsa-mir-1249-5p ; hsa-mir-1275 ; hsa-mir-1343-5p ; hsa-mir-147a ; hsa-mir-25-3p ; hsa-mir-3124-5p ; hsa-mir-3138 ; hsa-mir-3151-5p ; hsa-mir-3154 ; hsa-mir-3177-3p ; hsa-mir-3184-5p ; hsa-mir-363-3p ; hsa-mir-3650 ; hsa-mir-3654 ; hsa-mir-367-3p ; hsa-mir-3911 ; hsa-mir-423-5p ; hsa-mir-4324 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4489 ; hsa-mir-4520-3p ; hsa-mir-4524b-3p ; hsa-mir-4525 ; hsa-mir-4638-3p ; hsa-mir-4665-5p ; hsa-mir-4693-3p ; hsa-mir-4706 ; hsa-mir-4723-5p ; hsa-mir-4749-5p ; hsa-mir-4779 ; hsa-mir-5007-5p ; hsa-mir-5010-5p ; hsa-mir-503-3p ; hsa-mir-505-5p ; hsa-mir-5681b ; hsa-mir-5698 ; hsa-mir-6085 ; hsa-mir-6131 ; hsa-mir-625-5p ; hsa-mir-644a ; hsa-mir-6742-5p ; hsa-mir-6757-5p ; hsa-mir-6761-5p ; hsa-mir-6777-5p ; hsa-mir-6796-5p ; hsa-mir-6797-5p ; hsa-mir-6813-5p ; hsa-mir-6827-5p ; hsa-mir-6867-5p ; hsa-mir-6870-5p ; hsa-mir-6889-5p ; hsa-mir-7111-5p ; hsa-mir-765 ; hsa-mir-8071 ; hsa-mir-8485 ; hsa-mir-939-5p

Nearest miRNA

hsa-mir-1286/Upstream/244854; hsa-let-7a-3/Downstream/2580176;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/18886, chr22-CpG: 81/Downstream/38672

Upstream sequence

TATGGGGCAAAGGGAAAGGGGTGGGCATTAAGCCAAACCTGATGTCAGCCTGCCAGTAACCTCTGTTCAAAACCTCACAAGGCCAAGCACAATGACCGTG

Downstream sequence

TCCATTCTAAGCCGGGTCCAGCTATATCATGATGGTTGTATTTTTTTTTGttgtttttgttttttgtttttgctttttttgagacagagtctcgctctat