Basic Information
VIS ID
TVIS44011252
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
51035786/50597357 (Hg38)
End
51035786/50597357 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7a-3/Upstream/189833;
Nearest TSS
ENST00000624155/Upstream/205; ENST00000329492/Downstream/3328;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/13952, chr22-CpG: 103/Downstream/2708
Nearby gene
CHKB-DT(-2076) ; MAPK8IP2(+3328) ;
Upstream sequence
CTTTTCACTAATGTATCCCTGAGCTGCACAGAGCAGCCCTGGGGGACTGGGAGGACATGTCCCCGGTGTGAGGAGCAGGGGAAAGGTGAGCCTTAAATGA
Downstream sequence
TCACCAACAAACAACAGGGCCTGTGTCTGGGGCTTACACCACGACATGTGGTCCTCGCAGCAccattgctcagaggaagaaaccaagatctcgaggaact
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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