Basic Information
VIS ID
TVIS44011258
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
23981179/23939688 (Hg38)
End
23981179/23939688 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA3A
Nearest miRNA
hsa-mir-12127/Upstream/3802047; hsa-let-7g/Downstream/1725185;
Nearest TSS
ENST00000440867/Upstream/21983; ENST00000468700/Downstream/5572;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/21998, chr3-CpG: 165/Downstream/5472
Nearby gene
NR1D2(+5572) ;
Upstream sequence
aaattagctgggcatggtggcatgtgcctgtaatcccagctactcaggaggctgaggcaggagaatggcttgaacccaggaggaggtggaggttacagtg
Downstream sequence
agctgagatcgtgccactgcactccagtctgggtgacagagcgagactccgtctcaaaacaaacaaacaaacaaacaaaaaacaaaaaagggaaactgta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate