Basic Information
VIS ID
TVIS44011267
Fusion event
HTLV-1-LOC105377171 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
77996886/77947735 (Hg38)
End
77996886/77947735 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377171
Nearest miRNA
hsa-let-7g/Upstream/2209372; hsa-mir-12124/Downstream/1560152;
Nearest TSS
ENST00000440867/Upstream/312810; ENST00000461186/Downstream/99059;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/849487, chr3-CpG: 49/Downstream/1071178
Nearby gene
ROBO2(+297772) ;
Upstream sequence
TAAAGTGTACTATGATCCGTGAAGAAGCGCCAACAGCATATTTTAATTCAATAGAAAATTACCTCCACTGCTACTTTAAGGACAAACAAAACTAAGAAGG
Downstream sequence
GACTAATCTACATCTCCATGCTGTTGAAGATGTATGGTCATTTAGAGGAGATTTATGCTATTGAATATCTATTTTACAAGCTCTTCCAAGAACAGCATCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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