Basic Information
VIS ID
TVIS44011276
Fusion event
HTLV-1-MIR548G integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
99686115/99967271 (Hg38)
End
99686115/99967271 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR548G
Nearest miRNA
hsa-let-7g/Upstream/2873; hsa-mir-12124/Downstream/3556762;
Nearest TSS
ENST00000440867/Upstream/91068; ENST00000479555/Downstream/146993;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/90814, chr3-CpG: 22/Downstream/257989
Upstream sequence
CTCTTGGAATGTGTtcttggctcttagccccacctctgactttgagcaaatcagctgatttctctgcctgtaaaataatagtccctctgatattaatact
Downstream sequence
tacctcatgaggttatttagaggatAGTGTTGGTAATAATGCCTTGTGTTTACATCATTCCTTTCACAGAGAGCTCAAAGCACTTTACATGCATTGAGAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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