VISDB Viral Integration Site DataBase

VIS ID

TVIS44011287

Fusion event

HTLV-1-MBD4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q21.3

Reference genome

Start

End

129157559/129438716 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-486-3p ; hsa-mir-6825-5p ; hsa-mir-3175 ; hsa-mir-7106-5p ; hsa-mir-6721-5p ; hsa-mir-6878-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-765 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-3148 ; hsa-mir-4434 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6770-5p ; hsa-mir-1252-5p ; hsa-mir-4779 ; hsa-mir-651-3p ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-1273h-3p ; hsa-mir-3190-3p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-4289 ; hsa-mir-499b-5p ; hsa-mir-6888-5p ; hsa-mir-182-5p ; hsa-mir-1271-5p ; hsa-mir-183-5p ; hsa-mir-96-5p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-3653-3p ; hsa-mir-4650-3p ; hsa-mir-298 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-4530 ; hsa-mir-922 ; hsa-mir-1226-3p ; hsa-mir-196b-5p ; hsa-mir-6831-5p ; hsa-mir-196a-5p ; hsa-mir-3927-3p ; hsa-mir-634 ; hsa-mir-4662a-3p ; hsa-mir-15b-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-486-5p ; hsa-mir-500a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p

Nearest miRNA

hsa-let-7g/Upstream/166473; hsa-mir-1224/Downstream/2547139;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/9942, chr3-CpG: 81/Downstream/1043

Nearest cancer related gene

MBD4(TSG, No orient, 0)

Upstream sequence

AAAAGCTggcaaggcaaggtggctcattcctgtaatgctagcactttgggaggaggaagtgggaagatcacctgatcccaagagtttgagaccagcctgg

Downstream sequence

agagcacagtgagatcctcgtctttgcaaaaaatgaaaaaaaaaacccaaaaaaacaaaaaaaaacaagcaaccgggcgtggtggagcatacctgtggtc