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Viral Integration Site DataBase
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TVIS44011297
Basic Information
VIS ID
TVIS44011297
Fusion event
HTLV-1-SSR3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.31
Reference genome
GRCh37/hg19
Start
156263031/156545242 (Hg38)
End
156263031/156545242 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
SSR3
miRNAs that regulate target gene
hsa-mir-148b-3p
;
hsa-mir-132-3p
;
hsa-mir-122-5p
;
hsa-mir-615-3p
;
hsa-mir-125b-5p
;
hsa-mir-3177-3p
;
hsa-mir-335-3p
;
hsa-mir-498
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-4744
;
hsa-mir-186-3p
;
hsa-mir-583
;
hsa-mir-1276
;
hsa-mir-4311
;
hsa-mir-1305
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-3692-3p
;
hsa-mir-4753-3p
;
hsa-mir-6881-3p
;
hsa-mir-6780a-3p
;
hsa-mir-7111-3p
;
hsa-mir-6515-3p
;
hsa-mir-1236-3p
;
hsa-mir-125b-2-3p
;
hsa-mir-4259
;
hsa-mir-4715-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-3178
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6499-5p
;
hsa-mir-338-3p
;
hsa-mir-4530
;
hsa-mir-383-3p
Nearest miRNA
hsa-let-7g/Upstream/4979247; hsa-mir-1224/Downstream/2737404;
Nearest TSS
ENST00000440867/Upstream/20995;
ENST00000473702/Downstream/3755;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/253711
,
chr3-CpG: 49/Downstream/9605
Upstream sequence
GTTGGTTAATTAACTTTGTAAAGCAgtttttaaaagggtaggttgtgacccattagtgggatgtgaactcaatcaagtggatcgaatgcccatagaaatt
Downstream sequence
aattgagttgagaccagcattttaaaaaaatgaaataggaaagaatagaaaaacatcagcagcacatcgcacagagtaggataattatcgttttatgaaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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