Basic Information
VIS ID
TVIS44011331
Fusion event
HTLV-1-ENPEP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
111477892/110556736 (Hg38)
End
111477892/110556736 (Hg38)
Orient
+
Location type
Intronic
Target gene
ENPEP
miRNAs that regulate target gene
hsa-mir-320a ; hsa-mir-125b-5p
Nearest miRNA
hsa-mir-12113/Upstream/1067941; hsa-mir-1243/Downstream/303846;
Nearest TSS
ENST00000502981/Upstream/7308; ENST00000504100/Downstream/2372;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/79803, chr4-CpG: 29/Downstream/31001
Upstream sequence
tggtagaagtaatgctactgggtgaaaagatgtgtttatttttagggtttctgataaatgttgcagaattgccattctaaaaactgttgctagtaactgc
Downstream sequence
ctatgttcccaacctttttcaatgctcagtgttgttatttttatgtatctttgttaattgaatatatgaaaactgatatctcattttaaattacatttct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate