Basic Information
VIS ID
TVIS44011340
Fusion event
HTLV-1-LOC101927490 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
140543196/139622042 (Hg38)
End
140543196/139622042 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4C
Target gene
LOC101927490
Nearest miRNA
hsa-mir-12113/Upstream/14114735; hsa-mir-1305/Downstream/3721418;
Nearest TSS
ENST00000502981/Upstream/15343; ENST00000502587/Downstream/1190;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/64568, chr4-CpG: 18/Downstream/76351
Nearby gene
MGST2(+43726) ;
Upstream sequence
ATTTTTCTGAACAGTCTAATGTATTTTTGCATGAATCTAACCAGTGTGTTTAATCTCTATTGGATTCTTTTCCCataaattattatattaaaatatatGT
Downstream sequence
CAGTTATATTTATACATTGCATGCTTGTGtatatttaaatatatattaaaataCCTCTGTGATTTGTATGGTCCATTTACATAGGCTGTCATTTATGAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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