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TVIS44011352
Basic Information
VIS ID
TVIS44011352
Fusion event
HTLV-1-CLCN3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q33
Reference genome
GRCh37/hg19
Start
170542765/169621614 (Hg38)
End
170542765/169621614 (Hg38)
Orient
-
Location type
Intronic
Target gene
CLCN3
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-15a-5p
;
hsa-mir-335-5p
;
hsa-mir-148b-3p
;
hsa-mir-548b-3p
;
hsa-mir-570-5p
;
hsa-mir-548m
;
hsa-mir-548ag
;
hsa-mir-548ai
;
hsa-mir-548ba
;
hsa-mir-4282
;
hsa-mir-183-3p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-4671-3p
;
hsa-mir-3201
;
hsa-mir-573
;
hsa-mir-3185
;
hsa-mir-3616-5p
;
hsa-mir-4635
;
hsa-mir-5582-3p
;
hsa-mir-195-3p
;
hsa-mir-16-2-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-3591-5p
;
hsa-mir-4473
;
hsa-mir-539-5p
;
hsa-mir-4484
;
hsa-mir-6768-3p
;
hsa-mir-548an
;
hsa-mir-1299
;
hsa-mir-206
;
hsa-mir-3182
;
hsa-mir-3668
;
hsa-mir-4782-5p
;
hsa-mir-516b-5p
;
hsa-mir-5706
;
hsa-mir-6128
;
hsa-mir-613
;
hsa-mir-875-3p
Nearest miRNA
hsa-mir-12113/Upstream/4235277; hsa-mir-1305/Downstream/1564570;
Nearest TSS
ENST00000502981/Upstream/1062;
ENST00000506924/Downstream/14369;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/955
,
chr4-CpG: 38/Downstream/136179
Upstream sequence
TTTGTATGGCATTTTAAAACTGCGGAGCATATAGAAGATAATTACATATGCATTGTGCATATTAGAAACTGAGATTTCTGTTTCCTTTAGAAAGAAATTC
Downstream sequence
CTGTTCATGGAATTGAATCAACAGCGACCATACCTTTTACACAGATATATAATTCAAAAGTTCAGTTCTACAAACGTAAACTTTTGGAGCTATGCAGTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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