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Viral Integration Site DataBase
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TVIS44011399
Basic Information
VIS ID
TVIS44011399
Fusion event
HTLV-1-ARL10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
175817941/176390940 (Hg38)
End
175817941/176390940 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
ARL10
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-142-3p
;
hsa-mir-128-3p
;
hsa-mir-16-5p
;
hsa-mir-7641
;
hsa-mir-5189-3p
;
hsa-mir-4695-3p
;
hsa-mir-3185
;
hsa-mir-3921
;
hsa-mir-4653-5p
;
hsa-mir-301b-5p
;
hsa-mir-301a-5p
;
hsa-mir-146a-3p
;
hsa-mir-7978
;
hsa-mir-3973
;
hsa-mir-4661-3p
;
hsa-mir-582-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-548l
;
hsa-let-7g-3p
;
hsa-let-7a-2-3p
;
hsa-mir-6739-5p
;
hsa-mir-3153
;
hsa-mir-6733-5p
;
hsa-mir-6770-5p
;
hsa-mir-7515
;
hsa-mir-5584-5p
;
hsa-mir-3154
;
hsa-mir-552-3p
;
hsa-mir-320e
;
hsa-mir-4429
;
hsa-mir-320d
;
hsa-mir-320c
;
hsa-mir-320b
;
hsa-mir-320a
;
hsa-mir-1305
;
hsa-mir-4275
;
hsa-mir-192-3p
;
hsa-mir-3688-3p
;
hsa-mir-8076
;
hsa-mir-5583-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-649
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-6836-3p
;
hsa-mir-5001-3p
;
hsa-mir-4279
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-4284
;
hsa-mir-3194-3p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-6778-3p
;
hsa-mir-2276-3p
;
hsa-mir-4638-5p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-1304-3p
;
hsa-mir-6741-3p
;
hsa-mir-6742-3p
;
hsa-mir-6852-5p
;
hsa-mir-939-3p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-660-3p
;
hsa-mir-6890-3p
;
hsa-mir-122-3p
;
hsa-mir-6796-3p
;
hsa-mir-665
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-526b-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-7160-5p
;
hsa-mir-873-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-4649-3p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-3156-5p
;
hsa-mir-1273a
;
hsa-mir-1273c
;
hsa-mir-1273g-3p
;
hsa-mir-4252
;
hsa-mir-4486
;
hsa-mir-4649-5p
;
hsa-mir-4793-3p
;
hsa-mir-508-5p
;
hsa-mir-6729-5p
;
hsa-mir-7-1-3p
;
hsa-mir-7-2-3p
;
hsa-mir-766-3p
;
hsa-mir-7703
Nearest miRNA
hsa-mir-10397/Upstream/22909; hsa-mir-1229/Downstream/238499;
Nearest TSS
ENST00000502646/Upstream/1965;
ENST00000506061/Downstream/15400;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/1493
,
chr5-CpG: 91/Downstream/25177
Nearby gene
HIGD2A
(+1190) ;
Upstream sequence
GAGATTTGTGTACATAGTGTTTGAGGGTTCTGGAAGAGGAGGCTGAGGACCTGAGCACACTCTAGAAGAGAGGTGACCTGTTAGTTCCTCCTTCATGTAG
Downstream sequence
TTTCAAACAAGTATTCCTGGTCTGTGGTCAGCGCTCCTCAAATGTTGGATTTGAGGACCTGCGCTCTTCCCGAGTGATTGTACTGTTTTCAACACCAGCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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