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Viral Integration Site DataBase
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TVIS44011416
Basic Information
VIS ID
TVIS44011416
Fusion event
HTLV-1-KIF6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
39560757/39592981 (Hg38)
End
39560757/39592981 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
KIF6
miRNAs that regulate target gene
hsa-mir-339-5p
;
hsa-mir-125a-5p
;
hsa-mir-6515-5p
;
hsa-mir-6807-5p
;
hsa-mir-4443
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-8077
;
hsa-mir-496
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1233-3p
;
hsa-mir-1225-3p
;
hsa-mir-135b-5p
;
hsa-mir-135a-5p
;
hsa-mir-889-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-4776-3p
;
hsa-mir-192-3p
;
hsa-mir-661
;
hsa-mir-3116
;
hsa-mir-1254
;
hsa-mir-5189-3p
;
hsa-mir-4772-5p
;
hsa-mir-4748
;
hsa-mir-4464
;
hsa-mir-3591-3p
;
hsa-mir-21-3p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-6501-3p
;
hsa-mir-6715a-3p
;
hsa-mir-6760-5p
;
hsa-mir-4701-5p
;
hsa-mir-5089-5p
;
hsa-mir-5589-5p
;
hsa-mir-6506-5p
;
hsa-mir-4731-5p
;
hsa-mir-619-5p
;
hsa-mir-512-3p
;
hsa-mir-4433b-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-6801-5p
;
hsa-mir-6780b-5p
;
hsa-mir-4725-3p
;
hsa-mir-4271
;
hsa-mir-671-5p
;
hsa-mir-4313
;
hsa-mir-345-3p
;
hsa-mir-6798-5p
;
hsa-mir-6718-5p
;
hsa-mir-203b-5p
;
hsa-mir-6783-5p
;
hsa-mir-3943
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-7157-5p
;
hsa-mir-4310
;
hsa-mir-186-5p
;
hsa-mir-3133
Nearest miRNA
hsa-mir-1236/Upstream/518600; hsa-mir-10398/Downstream/2005742;
Nearest TSS
ENST00000381078/Upstream/161607;
ENST00000405961/Downstream/3279;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/278542
,
chr6-CpG: 34/Downstream/131986
Upstream sequence
GTAATTATAATGCTGCATGGAATTTGTGGAACCAATGTAGGCTAATTAAGGTAAAGCAAGTTACCAAATGGTTTCCCATTCCATCTCTGTCTTATATATT
Downstream sequence
GAAACCGAGAGAGGGGATAGGGATATAATTGATTACCAACACTCACATGGATTTCTATTATAGGTTTTAAATTACTATATTGCTAAGTATTTATTTGTAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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