Basic Information
VIS ID
TVIS44011422
Fusion event
HTLV-1-LOC101927293 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
58420430/58094152 (Hg38)
End
58420430/58094152 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC101927293
Nearest miRNA
hsa-mir-10398/Upstream/703940; hsa-mir-10524/Downstream/13282808;
Nearest TSS
ENST00000381078/Upstream/55686; ENST00000622616/Downstream/2628996;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/132602, chr6-CpG: 45/Downstream/4191798
Upstream sequence
attacacaaaaattcActttctgcccttccctttctgcctaaaagcaaggcataaatttccctttgtaaaggtgagataagttcctatttgtaaaggtgt
Downstream sequence
tcccgtgtcctgtaccaggaagaccagaaacagcactgagatgagactgcataacaaaccttactaaacattctgtatctaccatacatttcctagtacc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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