Basic Information
VIS ID
TVIS44011429
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
72558944/71849241 (Hg38)
End
72558944/71849241 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6D
Nearest miRNA
hsa-mir-10398/Upstream/445620; hsa-mir-10524/Downstream/1118446;
Nearest TSS
ENST00000381078/Upstream/398407; ENST00000370419/Downstream/37462;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/260416, chr6-CpG: 64/Downstream/37092
Nearby gene
RIMS1(+37462) ;
Upstream sequence
TTTTTTATGATTCATGCATCTGAGTACACAAGCCaattatttatatttgttaattaaacaattattattattaattGAATGTTCAAATAACAAGTGGAAG
Downstream sequence
TTCTCCATCATTTGCCCTAACATTCAAGATGAACTTTAAGGTAATATTGAAACCTTAAGGTACTATTTTCATTGTGAAAATGGATAGGAAATATAGTTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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