Basic Information
VIS ID
TVIS44011432
Fusion event
HTLV-1-LOC105377862 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
77666425/76956708 (Hg38)
End
77666425/76956708 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377862
Nearest miRNA
hsa-mir-10398/Upstream/1528235; hsa-mir-10524/Downstream/1582555;
Nearest TSS
ENST00000381078/Upstream/181725; ENST00000602452/Downstream/507065;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1207158, chr6-CpG: 132/Downstream/505806
Nearby gene
HTR1B(-504140) ;
Upstream sequence
CAATTTTAATATAAATATATCACTGTTCTTTACTCTGTATTGACTGACTATTTTTATATACACTGGCTCTTAATACCTGTTATAGTATtattggaggata
Downstream sequence
gaatgatcatcattgagattatgaagtgtcaaaacatgataaaatgcttaccttaaataacgtaaaaggaacatggtgtctctaatgagtctgtgacttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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