Basic Information
VIS ID
TVIS44011449
Fusion event
HTLV-1-LOC107986665 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q26
Reference genome
GRCh37/hg19
Start
161286853/160865821 (Hg38)
End
161286853/160865821 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986665
Nearest miRNA
hsa-mir-10398/Upstream/2101068; hsa-mir-1913/Downstream/5643533;
Nearest TSS
ENST00000381078/Upstream/126653; ENST00000420601/Downstream/14573;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/98214, chr6-CpG: 28/Downstream/65231
Nearby gene
PLG(+111768) ;
Upstream sequence
CAAGACTCGCATCCCAGGTGGTTGTTGGAAGAAAAATCCCATTTACCCTCTACCGAGGCTGAGGGAGAAAGACTGAAAAACAGCATGGCTTAAGGGAACT
Downstream sequence
CAGGAGGTCTTCTGTGCCTCCCAAAGATCTTGCCAACCGGGTGGCCAAACCTTAGATATTTTTCCAGTTAGCATTCCCCAAAAACCCCACAAGGAGTACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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