Basic Information
VIS ID
TVIS44011458
Fusion event
HTLV-1-LOC646588 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
25801976/25762356 (Hg38)
End
25801976/25762356 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC646588
Nearest miRNA
hsa-mir-1183/Upstream/4291210; hsa-mir-10399/Downstream/187563;
Nearest TSS
ENST00000635602/Upstream/11362; ENST00000607375/Downstream/187047;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/581991, chr7-CpG: 67/Downstream/89980
Nearby gene
MIR148A(-187563) ;
Upstream sequence
AATAAtttgagctgagttttcagtacttgcagcagaaagactctgacctgatacaGAGGGATAGATACACAGGTAATCACAATGCAATGTGATAAATCTT
Downstream sequence
AATGTGAAAAGAAAAATAAAGTGCTTTGGGAGTTGTGGACAGTCAGTGTTGCTTCTTTGGTTCTTCGTTGGTAAAATGGCTCACCTGCCTAGATAACAAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate