Basic Information
VIS ID
TVIS44011462
Fusion event
HTLV-1-PDE1C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
32461054/32421442 (Hg38)
End
32461054/32421442 (Hg38)
Orient
+
Location type
Intronic
Target gene
PDE1C
Nearest miRNA
hsa-mir-1183/Upstream/2131552; hsa-mir-10399/Downstream/311539;
Nearest TSS
ENST00000635602/Upstream/122113; ENST00000645498/Downstream/6459;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/122329, chr7-CpG: 57/Downstream/6380
Nearby gene
LOC100130673(-35456) ;
Upstream sequence
TGGAAGAATCATCATGGCATTGTGGAAGGAGAACTGGATTACAAATCAGATTCACCTACACGGATGATCCGTTAATGTGTGTGtaaccaatattgactaa
Downstream sequence
atgactagcaagtcccaaggcatgtgccaagtaccttgcataaattgccttatttaggtgagatcaatacaatttccattttccagatcagaaaatgggc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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