Basic Information
VIS ID
TVIS44011472
Fusion event
HTLV-1-LOC105375341 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
67778413/68313426 (Hg38)
End
67778413/68313426 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
LOC105375341
Nearest miRNA
hsa-mir-1183/Upstream/1199029; hsa-mir-10399/Downstream/2994246;
Nearest TSS
ENST00000635602/Upstream/25193; ENST00000447158/Downstream/726726;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1010382, chr7-CpG: 226/Downstream/1283962
Nearby gene
LOC102723427(No orient, 280736)
Upstream sequence
ATTTTATGCCAATGTTAGtgttactggtggagggtgtccaggttcttgacctcttgaacaaggaattggacaaaacgcacaaacagaacaaggaaagaat
Downstream sequence
gaagcaataaaagtagagatttattaaaaatgaaaatatgctccacagggtgggagcgggtccaagcacaggggctcaagatccccgttatccagaattt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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