Basic Information
VIS ID
TVIS44011479
Fusion event
HTLV-1-LOC100630923 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
102046536/102406089 (Hg38)
End
102046536/102406089 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA7F
Target gene
LOC100630923
Nearest miRNA
hsa-mir-10525/Upstream/234; hsa-mir-10399/Downstream/59653;
Nearest TSS
ENST00000635602/Upstream/1732; ENST00000482237/Downstream/27017;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/9519, chr7-CpG: 78/Downstream/27069
Upstream sequence
gtggtagtcggttggcaagaagtcaggtgaatatggtggatgaggcaacacatcgcagcccaatttgttcaacctttgaagcattggttgtgtgactcgt
Downstream sequence
ggtcgggcattgtcctggggaagaattgggccccttctgttgatcagtgctggctgcaggcattggagttttcagtgcatctcatcgatttgctgcacat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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