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Viral Integration Site DataBase
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TVIS44011492
Basic Information
VIS ID
TVIS44011492
Fusion event
HTLV-1-MYOM2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
2065031/2117241 (Hg38)
End
2065031/2117241 (Hg38)
Orient
+
Location type
Intronic
Target gene
MYOM2
miRNAs that regulate target gene
hsa-mir-4684-5p
;
hsa-mir-98-3p
;
hsa-let-7f-1-3p
;
hsa-let-7b-3p
;
hsa-let-7a-3p
;
hsa-mir-3675-3p
;
hsa-mir-4666a-3p
;
hsa-mir-381-3p
;
hsa-mir-300
;
hsa-mir-6771-3p
;
hsa-mir-1227-3p
;
hsa-mir-1273h-5p
;
hsa-mir-149-3p
;
hsa-mir-204-3p
;
hsa-mir-2467-3p
;
hsa-mir-30b-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-30c-2-3p
;
hsa-mir-3122
;
hsa-mir-3165
;
hsa-mir-3622a-3p
;
hsa-mir-3622b-3p
;
hsa-mir-3665
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-3714
;
hsa-mir-377-5p
;
hsa-mir-3913-5p
;
hsa-mir-4257
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-450a-1-3p
;
hsa-mir-4537
;
hsa-mir-455-3p
;
hsa-mir-4646-5p
;
hsa-mir-4728-5p
;
hsa-mir-4736
;
hsa-mir-4747-5p
;
hsa-mir-4768-3p
;
hsa-mir-490-3p
;
hsa-mir-5196-5p
;
hsa-mir-544b
;
hsa-mir-6086
;
hsa-mir-6499-3p
;
hsa-mir-6513-5p
;
hsa-mir-6516-5p
;
hsa-mir-6765-3p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6788-5p
;
hsa-mir-6799-5p
;
hsa-mir-6808-5p
;
hsa-mir-6828-5p
;
hsa-mir-6883-5p
;
hsa-mir-6893-5p
;
hsa-mir-7106-5p
;
hsa-mir-7162-3p
;
hsa-mir-7851-3p
;
hsa-mir-887-5p
;
hsa-mir-940
Nearest miRNA
hsa-mir-3674/Upstream/40601; hsa-mir-10400/Downstream/4504883;
Nearest TSS
ENST00000518652/Upstream/7954;
ENST00000520072/Downstream/1624;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/18108
,
chr8-CpG: 37/Downstream/10339
Upstream sequence
ACATTCATTTTTATTATTTTTCATTGTTTTTATTTCTAATAGTCACAAATATTTTACTTACTTCTACATTATGAACATTTTTGGGCCAACTTTGTAGGAT
Downstream sequence
GTATTTATGTATATGAAAGAAGTGACACATACTTTCCAAATCTGCTTTGTATTTTTGCATTGAATGGCAAAAGGGTATTAGTGTATGACTTATTCCTACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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