Basic Information
VIS ID
TVIS44011521
Fusion event
HTLV-1-LY96 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
74976970/74064735 (Hg38)
End
74976970/74064735 (Hg38)
Orient
+
Location type
Intronic
Target gene
LY96
Nearest miRNA
hsa-mir-124-1/Upstream/9685478; hsa-mir-10400/Downstream/483808;
Nearest TSS
ENST00000518652/Upstream/12395; ENST00000522498/Downstream/38781;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/88045, chr8-CpG: 52/Downstream/250371
Nearby gene
LY96(+35663) ;
Upstream sequence
caccagaagcagatggtggtgccaggcttcctatacagcctgcagaactgggagcccaataaacctcttttctctataaattacccagcctctgatattc
Downstream sequence
ctttatagcaatacaaatggactgatataatgtatcaacatggttaagtctcaaaaatgcaaaaagtgagaaaaatgtaaatcacagaagaagacacaca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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