Basic Information
VIS ID
TVIS44011556
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
32537521/32537523 (Hg38)
End
32537521/32537523 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA9C
Nearest miRNA
hsa-mir-101-2/Upstream/3648568; hsa-let-7a-1/Downstream/571169;
Nearest TSS
ENST00000422679/Upstream/11199; ENST00000450093/Downstream/13621;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/11097, chr9-CpG: 146/Downstream/13038
Nearby gene
TOPORS(-3021) ;
Nearest cancer related gene
TOPORS(TSG, -3021) ;
Upstream sequence
GGGCATGTATTACCTCATCTTAATGCATCTACCCACAAATGCTTTTTTGTCTATTTTTACCTCCTGCCATTTTATAGTAAGACTTGCCTTTGCTTGTCCA
Downstream sequence
TTGCTAATTTCATTTCTCTGTGCTCTGGACCATCTTTCTCATTCAGGAACTTTGTTTCATTAGTCAACCTTTCCTTCTCAAGGGGCTCTCTTCCAAAAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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