Basic Information
VIS ID
TVIS44011659
Fusion event
HTLV-1-SLC5A4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
32690436/32294449 (Hg38)
End
32690436/32294449 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC5A4
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1286/Upstream/672918; hsa-let-7a-3/Downstream/1142133;
Nearest TSS
ENST00000624155/Upstream/9766; ENST00000397468/Downstream/48656;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/117911, chr22-CpG: 36/Downstream/117389
Nearby gene
SLC5A4(-39118) ;
Upstream sequence
ttattctgtgataattgcatatgcacatgcaattgtgagaagtagtacagagacattcttttacttggtttccttcagctgcaacatcttgcaaaactac
Downstream sequence
attacaatatcacaactaggatactgacatcaaaacacttgaagatacagggcatttccatcacaaggatccctcctgtggctctttgagagccacaccc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate