Basic Information
VIS ID
TVIS44011681
Fusion event
HTLV-1-MIR924HG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
37175353/39595389 (Hg38)
End
37175353/39595389 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MIR924HG
Nearest miRNA
hsa-mir-1-2/Upstream/1938174; hsa-mir-122/Downstream/26734;
Nearest TSS
ENST00000575820/Upstream/254751; ENST00000636983/Downstream/204929;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/2027724, chr18-CpG: 34/Downstream/246107
Upstream sequence
TATAGTGCTATAAAATAAAGATGATATTGGAGGGCAACCTGTTAGGTGACTGGTGACTGGTGAGTGATGAAGTTGCTGTTCGTTTCACTATTATTTGTGG
Downstream sequence
TATGAAGTCCTGATTTCTAATCTTAGCCATGATTCAGGGCCTATTAATGATGACAGGCCTAATTCCTCTTTAACTTCTTCCTCAACTTTCAAAATATAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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