Basic Information
VIS ID
TVIS44011696
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
86003897/86292855 (Hg38)
End
86003897/86292855 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11F
Nearest miRNA
hsa-mir-10392/Upstream/14457; hsa-let-7a-2/Downstream/1883647;
Nearest TSS
ENST00000527297/Upstream/15757; ENST00000532270/Downstream/9356;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/47380, chr11-CpG: 23/Downstream/81796
Nearby gene
LOC100289518(-7435) ; SETP17(+1933) ;
Upstream sequence
ttttttttttttttgccatgttgcctaggctggtcttgaactcctgggctccagtgattgagcctcggcctcccaaagtgctgggattacaggcgtgagc
Downstream sequence
caccTCACAGGCCTCAGGTTGTTCCTTTTGAAGTTTCAAAATGGTTGCTACAACTCCAAGTATCACCTTCAGATATGTCAAAGTACAGAGACAGAAAGTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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