Basic Information
VIS ID
TVIS44011718
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
65242093/65256418 (Hg38)
End
65242093/65256418 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/4638548; hsa-mir-12124/Downstream/1969046;
Nearest TSS
ENST00000440867/Upstream/81460; ENST00000472514/Downstream/124413;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/568137, chr3-CpG: 63/Downstream/100110
Nearby gene
MAGI1(-97813) ;
Upstream sequence
tgtagctatttgtatatctgtctgtgctttctcttagattataaattccttgaactaaaggacaaaatcttatctttgtattcccagtgttaggccctaa
Downstream sequence
gtaatgctcagtatgtgttgaatgaatgaatGAGAAATAAGTAACGGAATAAACTTCCAGGTGTATCTATGACTAATAAGCAATTATACGGAGACTTTCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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