Basic Information
VIS ID
TVIS44011724
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
21575680/21575449 (Hg38)
End
21575680/21575449 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/3003569; hsa-mir-10398/Downstream/5572177;
Nearest TSS
ENST00000381078/Upstream/51666; ENST00000244745/Downstream/17319;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1171897, chr6-CpG: 131/Downstream/11741
Nearby gene
SOX4(+18292) ;
Nearest cancer related gene
SOX4(OG, +18292) ;
Upstream sequence
gatgaggtttcaccatgttggccaggctggtctcgaactcctgacctaaaatgatccgcccccctcggtcttccaaagtgctgggattacaggtgtgagc
Downstream sequence
caccgcgtctggccataactttctatattactggatttgatgtattaatattttgttgaaaatttttgcctctgcgttcatgaggaattttggagtgtaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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