Basic Information
VIS ID
TVIS44011748
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p23
Reference genome
GRCh37/hg19
Start
14777217/14776986 (Hg38)
End
14777217/14776986 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6A
Nearest miRNA
hsa-mir-3691/Upstream/4337192; hsa-mir-10398/Downstream/1364570;
Nearest TSS
ENST00000381078/Upstream/177296; ENST00000474854/Downstream/244978;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/565473, chr6-CpG: 113/Downstream/467660
Nearby gene
JARID2(+468989) ;
Upstream sequence
CATCATACCCAATTAGGCAAAAACAGACAAGAAAATCCAATTCTCTCCTCTTTCCTTCCTCCTTTATACTGAACTGCGACTAAAAGCAGCACTCACTATT
Downstream sequence
AGTGATACTAATTTGGTACTTAATTATCCTCAGGCTTCTGTCTTCCCCTAAATCTGTTCACCCTTTACCTCTGCACTTTGTCACCAATAACTGACTAGAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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