Basic Information
VIS ID
TVIS44011785
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
232413957/232278211 (Hg38)
End
232413957/232278211 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/1258287; hsa-mir-1537/Downstream/1345941;
Nearest TSS
ENST00000473358/Upstream/98098; ENST00000430921/Downstream/124555;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/650842, chr1-CpG: 173/Downstream/351131
Nearby gene
SIPA1L2(-119755) ;
Upstream sequence
tgttgaggggttgtatctagtgacagccttcttgctggtggggactgtctgaagagttccaaggctgggcagggtgtaggggtcaagtgtgctaatgtgc
Downstream sequence
taactcaggtctctattcttcttcttataaggccaccgctttccctcccatgataacccattagcctagcccattaatgcattaattcatgagtggatta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate