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Viral Integration Site DataBase
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TVIS44011795
Basic Information
VIS ID
TVIS44011795
Fusion event
HTLV-1-ZDHHC5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
57438780/57671308 (Hg38)
End
57438780/57671308 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZDHHC5
miRNAs that regulate target gene
hsa-mir-32-5p
;
hsa-mir-331-3p
;
hsa-mir-125b-5p
;
hsa-mir-25-3p
;
hsa-mir-92a-3p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-92b-3p
;
hsa-mir-4719
;
hsa-mir-7113-5p
;
hsa-mir-218-1-3p
;
hsa-mir-642b-5p
;
hsa-mir-4649-5p
;
hsa-mir-4685-5p
;
hsa-mir-6729-5p
;
hsa-mir-6837-5p
;
hsa-mir-190a-3p
;
hsa-mir-369-3p
;
hsa-mir-374a-5p
;
hsa-mir-656-3p
;
hsa-mir-374b-5p
;
hsa-mir-1277-5p
;
hsa-mir-3145-3p
;
hsa-mir-5011-5p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-6840-3p
;
hsa-mir-3941
;
hsa-mir-8485
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-599
;
hsa-mir-6844
;
hsa-mir-758-3p
;
hsa-mir-6808-3p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-642a-5p
;
hsa-mir-7973
;
hsa-mir-581
;
hsa-mir-5695
;
hsa-mir-519d-5p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-3691-3p
;
hsa-mir-29b-1-5p
;
hsa-mir-4446-5p
;
hsa-mir-3924
;
hsa-mir-3713
;
hsa-mir-4469
;
hsa-mir-4667-3p
;
hsa-mir-1470
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-153-5p
;
hsa-mir-1250-3p
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
Nearest miRNA
hsa-mir-129-2/Upstream/30022; hsa-let-7a-2/Downstream/1923769;
Nearest TSS
ENST00000527297/Upstream/2858;
ENST00000532842/Downstream/1836;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/2634
,
chr11-CpG: 66/Downstream/40706
Upstream sequence
GTCACCAGATAATGTGAGTAAAGTGCTTTTAGATCACCAGATGAAAAGCATTTTATAAAATCCCAAGGTGCTGGTGTTAGTTTGTTATTGTCATCAACAG
Downstream sequence
AAATAATTGTTACTTTTAATCATATTGGGGCAGGTGGGGCTCAGTTACCTTAGGCCAATATAGGAATAATAAACTGTTGAATTGGGAAAAAAGAACCAAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL39
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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