Basic Information
VIS ID
TVIS44011827
Fusion event
HTLV-1-LOC105370832 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
56842418/56550220 (Hg38)
End
56842418/56550220 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370832
Nearest miRNA
hsa-mir-10393/Upstream/1177186; hsa-mir-11181/Downstream/2620963;
Nearest TSS
ENST00000557528/Upstream/85083; ENST00000621974/Downstream/79345;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/85035, chr15-CpG: 88/Downstream/182979
Nearby gene
ZNF280D(-79956) ;
Upstream sequence
AAGGTGAGCACTATAAATGACCACTCCCTGGACCACACTCCTCCTTGTGCATTTCCTGAAGAAAAGGGAGGTGAACAAGAAGACAGGAAATGGGAAAACA
Downstream sequence
TCCTAGACAAAATAAAATAGCCACCACGATCCAATATTTTCATCATGCTCTTTCTGATAATAATATTCCTGAGAATATATCCCAAGAAGTAAGTTGAAAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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