Basic Information
VIS ID
TVIS44011868
Fusion event
HTLV-1-BAGE integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
11063456/10448999 (Hg38)
End
11063456/10448999 (Hg38)
Orient
-
Location type
Intronic
Target gene
BAGE
Nearest miRNA
hsa-mir-10396a/Upstream/1461334; hsa-let-7c/Downstream/2957385;
Nearest TSS
ENST00000624081/Upstream/106262; ENST00000612957/Downstream/72554;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/43261, chr21-CpG: 159/Downstream/72044
Upstream sequence
tagattagactttaacatagctctcaaatgaggatattaagtagatatgaaataaataataacaatgatcggttttgattcaaacagacacataaaatac
Downstream sequence
acgcagatctctgaattccaaaaatagagaaaacatcctattcaaatgtacatagaattttcaaaaaaacttcacatgtatggtcataaagaaatgtcca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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