Basic Information
VIS ID
TVIS44011910
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
63746179/64450352 (Hg38)
End
63746179/64450352 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/4746649; hsa-mir-103a-1/Downstream/7719115;
Nearest TSS
ENST00000502646/Upstream/284190; ENST00000508162/Downstream/55905;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/284073, chr5-CpG: 73/Downstream/55602
Nearby gene
RGS7BP(+55595) ;
Upstream sequence
tgaggtaggaaccattattttcctaattttacacctgataaaaataagggtttgagtgattattcagtttttaaaaaataactagaggatagtggaatca
Downstream sequence
tgattcagacccaggcccagctaactctaaagttcacaatcttaactattctggtaatactTTTCACTTTTGTATAGACACAATAAAATATCTTACCACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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