Basic Information
VIS ID
TVIS44011918
Fusion event
HTLV-1-KHDRBS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
62953951/62244046 (Hg38)
End
62953951/62244046 (Hg38)
Orient
-
Location type
Intronic
Target gene
KHDRBS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10398/Upstream/4853834; hsa-mir-10524/Downstream/9132914;
Nearest TSS
ENST00000381078/Upstream/1520898; ENST00000370659/Downstream/42181;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/4282496, chr6-CpG: 45/Downstream/41904
Upstream sequence
ttttttgaattttctagagtatatcaagtattattttcctctttaatcaattagtgtgataaattctatgaatcgtatttctaatgttgagtcattctgt
Downstream sequence
cagtcttagaacaaaacaaaaacaaaacaaaacattgcctgctcctgtcatctgctactttaaaaaagattcctgagtttgccaacagtttatgtagggt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate